Botox & Xeomin are trade names for botulimun toxin, which comes in the form of a purified protein. The mechanism of action for Botox/Xeomin is really quite simple. Botox/Xeomin is injected into the facial muscles but really doesn't affect the muscle at all. Botulinum toxin affects and blocks the transmitters between the motor nerves that innervate the muscle. There is no loss of sensory feeling in the muscles. Once the motor nerve endings are interrupted, the  muscle cannot contract. When that muscle does not contract, the dynamic motion that causes wrinkles in the skin will stop. The skin then starts to smooth out, and in approximately three to ten days after treatment, the skin above those muscles becomes nice and smooth. The effects of Botox/Xeomin last approximately three to four months, at which time the patient needs treatment.

The areas that botulimun toxin is commonly used for smoothing of facial wrinkles are the forehead, between the eyes (the 11's), around the corners of the eyes (crow's feet) and around the lips.

Botox/Xeomin also has important clinical uses as an adjunct in TMJ and bruxism (clenching & grinding) cases, and for patients with chronic TMJ and facial pain. It is also used to complement esthetic dentistry cases, as a minimally invasive alternative to surgically treating high lip line cases (gummy smile), denture patients who have trouble adjusting to new dentures, and lip augmentation.